Correlations between echocardiography left ventricular hypertrophy cardiovascular risk factors and 24 hour monitoring blood pressure results in hypertensive patients

Introduction: The left ventricular hypertrophy is the most important component of the hypertensive cardiomyopathy, with a high predictive value for the morbidity and mortality in chronic cardiovascular diseases. This study aims to highlight the correlations between the 24 hour values of blood pressure measured by ABPM and the left ventricular hypertrophy (LVH) in association with the cardiovascular risk factors in patients known with arterial hypertension. Methods: 237 patients were analyzed. They were hospitalized in the Clinic of Cardiovascular Rehabilitation of the Clinical Hospital of Rehabilitation Iași, during January 2012 – December 2013. Th e following parameters were evaluated: sex, age, body mass index, waist circumference, smoking habits, ethanol consumption, obesity, and diabetes and lipid profile. Each patient received a 24 hour ABPM monitoring and an echocardiography for determining the left ventricular mass index (LVMI). The study compared patients with and without LVH, considering that LVH is defined as LVMI > 95 g/m² in women and > 115 g/m² in men. Statistical analysis was performed in SPSS Statistics 20. Results: Average age was 58.79 ± 9.84 years, 39.6% male. 75.1% of patients presented LHV. Patients with LHV were older (59.93 ± 9.46 vs 55.37 ± 10.23 years, p < 0.001). Th e degree of hypertension was signifi cantly hi gher in the LHV group (p = 0.05). Paradoxically, in the group of patients without LVH, the prevalence of acti ve smokers was higher (17.2% vs 7.3%, p = 0.01). Ejection fraction was signifi cantly lower in the LHV patients (p = 0.001). No statistically significant correlations were recorded between the two groups in terms of obesity, diabetes, lipid parameters or ABPM. In the sub group analysis, strong correlations were recorded be tween the LHV and the elevated BP at ABPM in women patients (average SBP p = 0.002, average DBP p = 0.03, total hypertensive load p = 0.03). Conclusions: The results of the study correspond to the literature data. The prevalence of LVH increases with age and degree of hypertension. LVH is associated with a lower ejection fraction. Th e BP values, measured using ABPM, correlate with LHV only in the group represented by the female gender. Future studies should focus on examining the influence of gender on the LHV associated with arterial hypertension.

ISSN – online: 2734 – 6382
ISSN-L 1220-658X
ISSN – print: 1220-658X
The Romanian Journal of Cardiology is indexed by:
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CODE: 379
CME Credits: 10 (Romanian College of Physicians)