Excess immunity seriously damages health

Introduction: Takayasu’s arteritis is a rare, chronic in-flammatory disease of unknown origin, affecting usu-ally the walls of the aorta and its main branches. The in-flammation of the arteries may lead to stenosis, occlusi-ons, dilatations, and aneurysms of involved vessels. It is relatively common in Asia and the Far East but is rare in the Western Hemisphere.

Methods: We present the case of a 36-year-old woman with a history of type 1 diabetes mellitus and chronic autoimmune thyroiditis who presented with severe systemic hypertension and right hemiparesis. Physical exam revealed absent arterial pulses in the left upper limb and both inferior limbs and audible bruits over ri-ght subclavian and both common carotid arteries. An-giography revealed complete or subtotal obliteration of the aortic arch’s branches, stenosis of the descendent thoracic aorta, of the abdominal aorta and of both re-nal arteries. Intra-luminal angioplasty of the left renal artery was performed, followed by stenting. The right hypoplasic renal artery and atypical coarctation of the abdominal aorta remained unresolved.

Results: The outcome was favourable, the patient being discharged with controlled values of the blood pressu-re.

Conclusions: Takayasu´s arteritis is a severe, life threa-tening disease. Its association with multiple autoimmu-ne disorders seems to be rare, which makes this case more interesting, but worsens the prognosis.

ISSN – online: 2734 – 6382
ISSN-L 1220-658X
ISSN – print: 1220-658X
The Romanian Journal of Cardiology is indexed by:
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CODE: 379
CME Credits: 10 (Romanian College of Physicians)