Left venticle diastolic function depending on the type of hypertrophy secondary toarterial hypertension in patients with preserved systolic function

Introduction: Evaluate the diastolic function of the left ventricle in patients with high blood pressure in relation to type of left ventricular hypertrophy using conventional and tissue echocardiographic parameters. Methods: The study included patients with high blood pressure, left ventricular hypertrophy and preserved systolic function, and excluded patients with moderate and severe valvular pathology, rhythm disorders, ischemic heart disease, cardiomyopathy. The echocardiographic parameters used were: index of relative thickness ventricular wall, left ventricular mass, systolic wall stress, spectral and tissular mitral velocity, E/E’ ratio, isovolumetric relaxation time, systolic tissular velocity of mitral ring, in patients and normal group. Results: Evaluated 45 patients (24 women, 21 men), 58.6 ± 3.4 years old, left ventricular ejection fraction 56 ± 4%, divided in 2 groups: G1 – increased myocardial mass (MM) 178.49 ± 23.8 g and index > 0.45 and G2 – increased MM 182.58 ± 20.3 g and index < 0.45, A wave velocity in G1 = 0.78 ± 0.25 and in G2 = 0.67 ± 0.4 m/ sec, E/A ratio 0.7 ± 0.3, respectively 1.09 ± 0.5, systolic tissular velocities 0.09 ± 0.04 respectively 0.12 ± 0.03, E/E’ ratio 12 ± 3 respectively 8 ± 4. Conclusions: 1. The most common type of cardiac remodeling is concentric hypertrophy 68%, eccentric hypertrophy 32% 2. The gender distribution of concentric hypertrophy was equal. 3. The highest value of systolic wall stress was recorded at patients with concentric hypertrophy (2292 ± 560.8 dyne/cm2). 4. The anterograde mitral flow most commonly: delayed relaxation, associated mainly with concentric hypertrophy. 5. Concentric hypertrophy associated lowest systolic velocities, suggesting the installation of left ventricular systolic dysfunction, no detectable by conventional ultrasound. 6. E/E’ ratio higher in concentric hypertrophy mean increase filling pressures in left ventricular in concentric hypertrophy.

ISSN – online: 2734 – 6382
ISSN-L 1220-658X
ISSN – print: 1220-658X
The Romanian Journal of Cardiology is indexed by:
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CODE: 379
CME Credits: 10 (Romanian College of Physicians)