The prognostic role of RV dysfunction in heart failure with reduced EF

Introduction: Pulmonary hypertension and RV dysfunction are found late in the progression of HF with reduced EF and are markers of a severe cardiac dysfunction. We wanted to evaluate their prognostic value for the patient with HF. Methods: We examined 100 pts with HF with reduced EF and we determined disease duration, the probable cause, LV volumes, LV –EF, severity of diastolic dysfunction, systolic PAP and parameters of RV function – TAPSE, TVI (RVOT), S’, e’, a’ measured at lateral tricuspid annulus, tricuspid E/A value. We determined the number of rehospitalisations/deaths during 1 year. Results: 61 pts had new hospitaliations (85.24%) or died (14.75%) during 1 year. The pts who were hospitalised more often had significantly lower values of TAPSE: 13.2 mm vs 14 mm (p = 0.004), TVI (RVOT) 16.3 cm vs 18 cm (p = 0.04), S’ 11.3 cm/s vs 12.8 cm/s (p = 0.04). PAP value > 50 mm Hg and restrictive type diastolic dysfunction were more frequent in the group with more hospitalisations, while LV- EF did not differ. TVI (RVOT) and pulmonary hypertension are independent predictors of rehospitalisation in HF. Conclusions: Conclusion RV dysfunction which is correlated with pulmonary hypertension produces a suplimentary reduction in cardiac output and has a negative prognostic value in HF.

ISSN – online: 2734 – 6382
ISSN-L 1220-658X
ISSN – print: 1220-658X
The Romanian Journal of Cardiology is indexed by:
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CODE: 379
CME Credits: 10 (Romanian College of Physicians)